Protein phosphorylation is one of the most common and important post-translational modifications of proteins in the biological world, and has been regarded by biologists as a dynamic biomomomomomomomoto process since the 1950s. In cells, about one-third of proteins are thought to be modified by phosphorylation.
The phosphorylation modification of proteins is closely related to a variety of biological processes, such as DNA damage repair, transcription regulation, signal conduction, apoptosis regulation, etc. The study of phosphorylation proteins and peptides can help people to explain the mechanism of the above process and further understand the nature of life activities. In recent years, with the continuous development of proteomics technology, the research of protein phosphorylation has been paid more and more attention.