The detection method of peptide drugs

- Aug 22, 2019-

Inverted high-efficiency liquid chromatography High-efficiency liquid chromatography has become the most commonly used method in drug quality analysis, with sensitive, accurate and fast characteristics, peptide substances are connected by multiple amino acids through peptide bonds, there is a certain hydrophobic, in reverse chromatography has a certain reservation, in reverse high-efficiency liquid chromatography can be effectively separated,

Now most of the substance analysis of polypeptide drugs uses high-efficiency liquid chromatography.

Capillary electrophoresis In addition to the use of traditional high-efficiency liquid chromatography method for the analysis of related substances, capillary electrophoresis for the analysis of peptide drugs also has a greater advantage, capillary electrophoresis and has the advantages of high-voltage electrophoresis and liquid chromatography, and inverted high-efficiency liquid chromatography of the hydrophobic separation mechanism, there are a variety of separation modes, with rapid analysis, High resolution, less sample dosage, easy operation, less consumption and so on.