What is Ipamorelin?

- Nov 07, 2019-

Ipamorelin is a synthetic growth hormone secretagogue, a peptide that stimulates the body to increase the natural production of growth hormone. Growth hormone (GH) is produced and released by the pituitary gland. Ipamorelin increases the production of this natural growth hormone in two different ways. First, the peptide amplifies the natural growth hormone release signal. This leads to an increase in growth hormone secretion. Second, it inhibits a hormone called somatostatin, also known as growth hormone inhibitory hormone (GHIH). Somatostatin causes the body to reduce its natural growth hormone output. By limiting the effects of somatostatin, Ipamorelin eliminates the barrier to increased growth hormone secretion, thereby increasing natural growth hormone levels. Unlike GHRP-6 and GHRP-2, Ipamorelin had no effect on auxin levels in vivo. This prevents it from increasing appetite, which is ideal for those who want to lose weight for a long time or keep their weight for long-term use in anti-aging.

Because Ipamorelin stimulates the body to produce growth hormone, the production of natural growth hormone does not stop like synthetic human growth hormone. Ipamorelin causes growth hormone secretion in a manner closer to the natural release pattern, causing growth hormone to be released in a "pulsed" manner rather than continuously increasing. This results in fewer side effects than synthetic hGH. Ipamorelin produces a smoother, less intense pro-growth hormone release pulse than most other hormone-releasing peptides, and lasts longer, resulting in an increase in growth hormone after administration for up to 3 hours.

The combination of Ipamorelin with a peptide such as Mod-GRF or CJC-1295 can achieve higher levels of natural growth hormone. These GHRH peptides have a complementary mechanism of action that affects different receptors in the pituitary than Ipamorelin. Therefore, when used in combination, higher growth hormone levels can be obtained. This can lead to higher performance enhancements such as faster muscle tissue growth and repair, better wound healing and recovery, faster fat metabolism (fat loss), and even greater anti-aging effects.