Effect Of Recombinant Human Growth Hormone?

- Jan 11, 2020-

Many people talk about "growth hormone" color change. When it comes to growth hormone, they think of side effects such as obesity, osteoporosis, hepatorenal toxicity, etc. they immediately refuse to treat or give up treatment, because they think "growth hormone is hormone and cannot be used". In fact, there are many kinds of hormones in the human body. Generally speaking, "hormones" refer to glucocorticoids and sex hormones, which are not suitable for long-term use. Although growth hormone is also called "hormone", it is totally different from glucocorticoid and sex hormone in origin, chemical structure, physiology and pharmacology, and it will not produce glucocorticoid or sex hormone like side effects.

What is the effect of recombinant human growth hormone? Qianyuan Biotechnology Co., Ltd. answers for you

Human growth hormone (hGH) is a peptide hormone secreted by the anterior pituitary of human body, which is composed of 191 amino acids. Growth hormone can stimulate the liver and other tissues to produce insulin-like growth factor (IGF-1) to play its physiological function, promote the growth of bone, promote the synthesis and metabolism of body and protein synthesis, promote the decomposition of fat, inhibit the use of glucose and make blood glucose rise. During puberty, growth hormone can further cause the rapid growth of height under the synergistic effect of sex hormone.

Under normal conditions, growth hormone is pulsed. GH secretion is regulated by GHRH and somatostatin produced by hypothalamus, and also affected by sex, age and circadian rhythm. Normal people usually have very little GH in their blood, only when they sleep deeply at night can they have several peaks. Therefore, the height of children who stay up late for a long time will be affected. Whether GH is deficient or not can not be determined by single blood sampling. Only through drug stimulation test (GH stimulation test) can the peak of GH secretion be measured. From the height of the peak to judge whether GH is lacking.