What Is Growth Hormone?

- Oct 29, 2019-

Growth hormone, also known as human growth hormone (hGH), is a commonly used peptide hormone for sports athletes. Growth hormone was originally used for the treatment of dwarfism. It has anabolic effects, can increase muscle mass, promote bone growth in childhood and adolescence, strengthen tendons and enlarge internal organs, so it is loved by athletes. The main reason for using growth hormone is to strengthen muscles and increase strength. In order to gain competitive advantage.


Growth hormone can promote human growth and regulate the metabolism of substances in the body. Growth hormone mainly promotes blood sugar by inhibiting the use of glucose in muscle and adipose tissue, and promoting gluconeogenesis in the liver and decomposition of glycogen. Growth hormone promotes fat breakdown and increases plasma free fatty acids. When hunger, insulin secretion is reduced, growth hormone secretion is increased, and blood glucose utilization is reduced and fat utilization is increased. At this time, plasma glucose and free fatty acid content increase.


When a child has congenital or acquired diseases that cause growth hormone deficiency or insufficient secretion, it can cause short stature, even dwarfism, and the growth of various tissues and organs throughout the body will be delayed. Therefore, parents should seek medical attention as soon as possible if they find that their child is abnormally tall.


What are the methods of growing taller?


Currently, common endocrine diseases that can be treated with growth hormone in pediatrics are: growth hormone deficiency, idiopathic short stature, small for gestational age, Turner syndrome, Prader-Willi syndrome, Noonan syndrome, and the like.


The effect of using growth hormone is affected by factors such as age at which treatment begins, basal height, bone age, nutrition, and genetics.


Growth hormone is an effective drug approved by the US Food and Drug Administration (FDA) and the China Food and Drug Administration (CFDA) for the treatment of children with short stature. Since the development of rhGH in 1985, the synthetic genetic recombinant human growth hormone has the same chemical structure as the growth hormone produced by the human pituitary gland, and the physiological and pharmacological effects are also consistent. As an alternative supplementary therapeutic drug, it can obviously promote the children of short stature. The height of the body grows and improves the growth and development of various organs and tissues throughout the body. Football Messi was short-lived due to lack of growth hormone at the age of 10 years old. At the age of 10, she was only 1.25 meters tall. It was because of the growth hormone that grew to 1.70 meters, which made the current generation of the king.


Growth hormone can only be replenished by injection. If it is only by oral growth hormone, it will be decomposed. Even if it is not decomposed by oral administration through certain methods, macromolecules cannot be absorbed through the gastrointestinal tract and cannot function. Currently used growth hormones include short-acting growth hormone and long-acting growth hormone. Growth hormone is available in both powder and water formulations.


Clinical application has been more than 30 years, and the available data show that the growth hormone is safe and the overall incidence of adverse reactions is low. The currently reported adverse reactions of GH treatment mainly include local transient reactions (redness or rash) at the injection site, symptoms of fluid retention (peripheral edema, joint pain or myalgia, benign intracranial hypertension). These side effects occur early and often with medication. Decreased in time, rarely affecting daily activities. Another cause of abnormal blood sugar, hypothyroidism, etc., and more can be relieved after stopping the drug.