H Cg 5000iu Human Chorionic G-Onadotropin Powder CAS 9002/61/3

H Cg 5000iu Human Chorionic G-Onadotropin Powder CAS 9002/61/3

CAS No:9002-61-3
Specifications:5000iu/vial and 3000iu/vial

Product Details

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CAS No:9002-61-3

Specifications:5000iu/vial and 3000iu/vial

Purity:

price:If you need Human Chorionic Gonadotropin 5000iu price list, please contact customer service. 

Storage conditions: Store at 2 - 7°C. Keep tightly closed. Store in a cool dry place.

Molecular weight:

Molecular formula:


HProduct description:

Human chorionic gonadotropin is a glycoprotein secreted by the trophoblast cells of the placenta and is composed of alpha and beta dimer glycoproteins. Human chorionic gonadotropin (HCG) alpha beta, synthesized by syncytiotrophoblast cells.


With molecular weight of 36700 glycoprotein hormone, alpha subunit is basically similar to FSH(follicle-stimulating hormone), LH(luteinizing hormone) and TSH(thyroid stimulating hormone) secreted by pituitary gland, so they can cross-react with each other, while the structure of beta subunit is not similar. The structure of beta-hcg is similar to that of beta-lh, but the last 24 amino acid extensions do not exist in beta-lh.Urine-derived products: In the body, human chorionic gonadotropin primarily distributes into the testes in males and into the ovaries in females. In the ovaries, HCG is concentrated in the fluid of the developing follicles. The metabolic fate of HCG has not been elucidated, but it is eliminated in a biphasic manner. HCG contains a mix of both the alpha and beta subunits. The terminal half-life is approximately 23 hours. After a single IM injection, roughly 10—12% of a dose is excreted unchanged in the urine within 24 hours and can be detected for up to 3—4 days.


Intramuscular Route: Urinary-derived human chorionic gonadotropin (HCG) is administered by the intramuscular (IM) route; however, one study has shown similar bioavailability with subcutaneous (SC) administration.2 Subjective observations in the literature have also supported the use of HCG by the SC route as equivalent to IM administration clinically.3 Serum concentrations of HCG are detectable within 2 hours of IM administration; peak concentrations are attained within 6 hours and persist for roughly 36 hours.


Subcutaneous Route: Urinary-derived human chorionic gonadotropin (HCG) is administered by the intramuscular (IM) route; however, one study has shown similar bioavailability with subcutaneous (SC) administration.2 Subjective observations in the literature have also supported the use of HCG by the SC route as equivalent to IM administration clinically.3


Special Populations

Hepatic Impairment: The pharmacokinetics, safety, and efficacy of human chorionic gonadotropin have not been established in patients with hepatic impairment.4


Renal Impairment: The pharmacokinetics, safety, and efficacy of human chorionic gonadotropin have not been established in patients with renal impairment.4


Indications: Human chorionic gonadotropin (HCG) is indicated for different reasons in men and women. HCG Injections are used in combination with other fertility drugs to increase a woman’s chance of pregnancy. In men or adolescent boys, HCG helps with the production of testosterone and sperm. HCG Injections are also used in male children with cryptorchidism, a specific birth problem of the testes.


Storage: Store dry powder at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Once reconstituted keep this medicine in a refrigerator between 36°F to 46°F (2°C to 8°C). Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain

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